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1

Anti-hypertensive Effects of Diminazene Aceturate: An Angiotensin- Converting Enzyme 2 Activator in Rats

L.A. De Maria, Marilda, D. Araújo, Liliane, A. Fraga-Silva, Rodrigo, A.S. Pereira, Letícia, J. Ribeiro, Heder, B. Menezes, Gustavo, Shenoy, Vinayak, K. Raizada, Mohan, J. Ferreira, Anderson

Journal:

Protein & Peptide Letters

Year:

2015

Language:

english

File:

PDF, 442 KB

english, 2015

2

The Antithrombotic Effect of Angiotensin-(1-7) Involves Mas-Mediated NO Release from Platelets

Fraga-Silva, Rodrigo Araújo, Pinheiro, Sergio Veloso Brant, Gonçalves, Andrey Christian Costa, Alenina, Nathalia, Bader, Michael, Souza Santos, Robson Augusto

Journal:

Molecular Medicine

Year:

2008

File:

PDF, 1.13 MB

2008

3

From Patients to Platelets and Back Again: Pharmacological Approaches to Glycoprotein VI, a Thrilling Antithrombotic Target with Minor Bleeding Risks

Martins Lima, Augusto, Martins Cavaco, Ana C., Fraga-Silva, Rodrigo A., Eble, Johannes A., Stergiopulos, Nikolaos

Journal:

Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 877 KB

english, 2019

4

Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases

Anderson J. Ferreira, Vinayak Shenoy, Yanfei Qi, Rodrigo A. Fraga-Silva, Robson A. S. Santos, Michael J. Katovich, Mohan K. Raizada

Journal:

Experimental Physiology

Year:

2011

Language:

english

File:

PDF, 525 KB

english, 2011

5

Mas Receptor Agonists as Novel Antihypertensive Agents

Quintao Savergnini, Silvia, Araujo Fraga-Silva, Rodrigo, Jose Ferreira, Anderson, Augusto Souza dos Santos, Robson

Journal:

Current Hypertension Reviews

Year:

2012

Language:

english

File:

PDF, 996 KB

english, 2012

6

Standardization and Validation of Fluorescence-Based Quantitative Assay to Study Human Platelet Adhesion to Extracellular-Matrix in a 384-Well Plate

Martins Lima, Augusto, Saint Auguste, Damian S., Cuenot, FranÃ§ois, Martins Cavaco, Ana C., Lachkar, Tom, Khawand, Cindy Marie Elodie, Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 4.06 MB

2020

7

Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice

Copin, Jean-Christophe, da Silva, Rafaela F, Fraga-Silva, Rodrigo A, Capettini, Luciano, Quintao, Silvia, Lenglet, Sébastien, Pelli, Graziano, Galan, Katia, Burger, Fabienne, Braunersreuther, Vincent,

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2013

Language:

english

File:

PDF, 594 KB

english, 2013

8

Apelin-13 treatment enhances the stability of atherosclerotic plaques

Fraga-Silva, Rodrigo Araujo, Seeman, Hugo, Montecucco, Fabrizio, da Silva, Analina Raquel, Burger, Fabienne, Costa-Fraga, Fabiana Pereira, Anguenot, Léa, Mach, François, dos Santos, Robson Augusto Sou

Journal:

European Journal of Clinical Investigation

Year:

2018

Language:

english

File:

PDF, 1.77 MB

english, 2018

9

Update on the role of angiotensin in the pathophysiology of coronary atherothrombosis

da Silva, Analina R., Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos, Montecucco, Fabrizio, Mach, François

Journal:

European Journal of Clinical Investigation

Year:

2015

Language:

english

File:

PDF, 449 KB

english, 2015

10

Follicular regulatory helper T cells control the response of regulatory B cells to a high-cholesterol diet

Burger, Fabienne, Miteva, Kapka, Baptista, Daniela, Roth, Aline, Fraga-Silva, Rodrigo A, Martel, Catherine, Stergiopulos, Nikolaos, Mach, FranÃ§ois, Brandt, Karim J

Journal:

Cardiovascular Research

Year:

2020

File:

PDF, 1.25 MB

2020

11

Treatment with CB 2 Agonist JWH-133 Reduces Histological Features Associated with Erectile Dysfunction in Hypercholesterolemic Mice

Fraga-Silva, Rodrigo Araujo, Costa-Fraga, Fabiana Pereira, Montecucco, Fabrizio, Faye, Younouss, Savergnini, Silvia Quintao, Lenglet, Sébastien, Mach, François, Steffens, Sabine, Stergiopulos, Nikolao

Journal:

Clinical & Developmental Immunology

Year:

2013

Language:

english

File:

PDF, 2.86 MB

english, 2013

12

Arginase inhibition prevents the low shear stress-induced development of vulnerable atherosclerotic plaques in ApoE−/− mice

Olivon, Vania C., Fraga-Silva, Rodrigo A., Segers, Dolf, Demougeot, Céline, de Oliveira, Ana M., Savergnini, Silvia S., Berthelot, Alain, de Crom, Rini, Krams, Rob, Stergiopulos, Nikos, da Silva, Rafa

Journal:

Atherosclerosis

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

13

Spectral imaging reveals microvessel physiology and function from anastomoses to thromboses

Wankhede, Mamta, Agarwal, Nikita, Fraga-Silva, Rodrigo A., deDeugd, Casey, Raizada, Mohan K., Oh, S. Paul, Sorg, Brian S.

Journal:

Journal of Biomedical Optics

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

14

New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis

Ferreira, Anderson J., Murça, Tatiane M., Fraga-Silva, Rodrigo A., Castro, Carlos Henrique, Raizada, Mohan K., Santos, Robson A. S.

Journal:

International Journal of Hypertension

Year:

2012

Language:

english

File:

PDF, 2.51 MB

english, 2012

15

Editorial (Thematic Issue: Novel Insights on Aortic Aneurysm)

Fraga-Silva, Rodrigo, Trachet, Bram

Journal:

Current Pharmaceutical Design

Year:

2015

File:

PDF, 86 KB

2015

16

Diminazene Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Injury

Fraga-Silva, Rodrigo A., Costa-Fraga, Fabiana P., Montecucco, Fabrizio, Sturny, Mikael, Faye, Younoss, Mach, François, Pelli, Graziano, Shenoy, Vinayak, da Silva, Rafaela F., Raizada, Mohan K., Santos

Journal:

The Journal of Sexual Medicine

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

17

Angiotensin II infusion into ApoE-/- mice: a model for aortic dissection rather than abdominal aortic aneurysm?

Trachet, Bram, Aslanidou, Lydia, Piersigilli, Alessandra, Fraga-Silva, Rodrigo A., Sordet-Dessimoz, Jessica, Villanueva-Perez, Pablo, Stampanoni, Marco F.M., Stergiopulos, Nikolaos, Segers, Patrick

Journal:

Cardiovascular Research

Year:

2017

Language:

english

File:

PDF, 1.87 MB

english, 2017

18

Incidence, severity, mortality, and confounding factors for dissecting AAA detection in angiotensin II-infused mice: a meta-analysis

Trachet, Bram, Fraga-Silva, Rodrigo A., Jacquet, Philippe A., Stergiopulos, Nikolaos, Segers, Patrick

Journal:

Cardiovascular Research

Year:

2015

Language:

english

File:

PDF, 625 KB

english, 2015

19

Novel Concept Enabling an Old Idea: A Flexible Electrode Array to Treat Neurogenic Erectile Dysfunction

Skoufias, Spyridon, Sturny, Mikaël, Fraga-Silva, Rodrigo, Papaioannou, Theodore G., Stergiopoulos, Nikolaos, Adamakis, Ioannis, Constantinides, Constantinos A.

Journal:

The Journal of Sexual Medicine

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

20

An Increased Arginase Activity Is Associated with Corpus Cavernosum Impairment Induced by Hypercholesterolemia

Fraga-Silva, Rodrigo A., Costa-Fraga, Fabiana P., Faye, Younoss, Sturny, Mikaël, Santos, Robson A.S., da Silva, Rafaela F., Stergiopulos, Nikolaos

Journal:

The Journal of Sexual Medicine

Year:

2014

Language:

english

File:

PDF, 591 KB

english, 2014

21

Treatment with sulphated galactan inhibits macrophage chemotaxis and reduces intraplaque macrophage content in atherosclerotic mice

Gomes Quinderé, Ana Luíza, Barros Benevides, Norma Maria, Pelli, Graziano, Lenglet, Sébastien, Burger, Fabienne, Carbone, Federico, Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos, Pagano, Sabrina, Be

Journal:

Vascular Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.87 MB

english, 2015

22

Diminazene Attenuates Pulmonary Hypertension and Improves Angiogenic Progenitor Cell Functions in Experimental Models

Shenoy, Vinayak, Gjymishka, Altin, Jarajapu, Yagna P., Qi, Yanfei, Afzal, Aqeela, Rigatto, Katya, Ferreira, Anderson J., Fraga-Silva, Rodrigo A., Kearns, Patrick, Douglas, Jane Yellowlees, Agarwal, De

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 977 KB

english, 2013

23

The Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas receptor axis: A potential target for treating thrombotic diseases

Fraga-Silva, Rodrigo, Da Silva, Danielle, Montecucco, Fabrizio, Mach, François, Stergiopulos, Nikolaos, da Silva, Rafaela, Santos, Robson

Journal:

Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

24

The Antithrombotic Effect of Angiotensin-(1-7) Involves Mas-Mediated NO Release from Platelets

Fraga-Silva, Rodrigo Araújo, Pinheiro, Sergio Veloso Brant, Gonçalves, Andrey Christian Costa, Alenina, Nathalia, Bader, Michael, Souza Santos, Robson Augusto

Journal:

Molecular Medicine

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

25

Opportunities for Targeting the Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Receptor Pathway in Hypertension

Fraga-Silva, Rodrigo Araujo, Ferreira, Anderson Jose, Santos, Robson Augusto Souza

Journal:

Current Hypertension Reports

Year:

2013

Language:

english

File:

PDF, 366 KB

english, 2013

26

An Oral Formulation of Angiotensin-(1-7) Reverses Corpus Cavernosum Damages Induced by Hypercholesterolemia

Fraga-Silva, Rodrigo A., Costa-Fraga, Fabiana P., Savergnini, Silvia Q., De Sousa, Frederico B., Montecucco, Fabrizio, da Silva, Daniele, Sinisterra, Ruben D., Mach, François, Stergiopulos, Nikolaos,

Journal:

The Journal of Sexual Medicine

Year:

2013

Language:

english

File:

PDF, 995 KB

english, 2013

27

The Protective Arm of the Renin Angiotensin System (RAS) || Mas Agonists

Fraga-Silva, Rodrigo A.

Year:

2015

Language:

english

File:

PDF, 353 KB

english, 2015

28

Age-related changes in vascular responses to angiotensin-(1-7) in female mice

Costa-Fraga, Fabiana P, Goncalves, Gleisy K, Souza-Neto, Fernando P, Reis, Adelina M, Capettini, Luciano AS, Santos, Robson AS, Fraga-Silva, Rodrigo A, Stergiopulos, Nikolaos, da Silva, Rafaela F

Journal:

Journal of Renin-Angiotensin-Aldosterone System

Year:

2018

Language:

english

File:

PDF, 905 KB

english, 2018

29

Editorial (Thematic Issue: Pharmacotherapy in Sexual Medicine: Novel Insights)

Fraga-Silva, Rodrigo

Journal:

Current Drug Targets

Year:

2015

Language:

english

File:

PDF, 87 KB

english, 2015

30

Performance Comparison of Ultrasound-Based Methods to Assess Aortic Diameter and Stiffness in Normal and Aneurysmal Mice

Trachet, Bram, Fraga-Silva, Rodrigo A., Londono, Francisco J., Swillens, Abigaïl, Stergiopulos, Nikolaos, Segers, Patrick, Kirchmair, Rudolf

Journal:

Year:

2015

Language:

english

File:

PDF, 3.34 MB

english, 2015

31

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

Miteva, Kapka, Baptista, Daniela, Montecucco, Fabrizio, Asrih, Mohamed, Burger, Fabienne, Roth, Aline, Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos, Mach, FranÃ§ois, Brandt, Karim J.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 4.40 MB

2020

32

CHARACTERIZATION OF THE ACE2/ANG-(1–7)/MAS RECEPTOR AXIS IN DIFFERENT SHEAR STRESS REGIONS

Luciano S Capettinini, Silvia Q Savergnini, Rodrigo A Fraga-Silva, Fabrizio Montecucco, François Mach, Nikos Stergiopulos, Robson RA Santos, Rafaela F da Silva

Journal:

Journal of Biomechanics

Year:

2012

Language:

english

File:

PDF, 205 KB

english, 2012

33

Varicocele percutaneous embolization outcomes in a pediatric group: 7-year retrospective study

Malekzadeh, Sonaz, Fraga-Silva, Rodrigo A., Morère, Pierre-Henri, Sorega, Alexandra, Produit, Stephan, Stergiopulos, Nikolaos, Constantin, Christophe

Journal:

International Urology and Nephrology

Year:

2016

Language:

english

File:

PDF, 416 KB

english, 2016

34

Anti-apoA-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

Montecucco, Fabrizio, Braunersreuther, Vincent, Burger, Fabienne, Lenglet, Sébastien, Pelli, Graziano, Carbone, Federico, Fraga-Silva, Rodrigo, Stergiopulos, Nikolaos, Monaco, Claudia, Mueller, Christ

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

35

Tollip Controls Atherogenesis Through Regulation of Autophagy-mediated Degradation of Low-density Lipoprotein Receptor

Baptista, Daniela, Roth, Aline, Burger, Fabienne, Fraga-Silva, Rodrigo, Stergiopulos, Nikolaos, Mach, François, Brandt, Karim J.

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 357 KB

english, 2018

36

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

Bragina, Maiia E., Costa-Fraga, Fabiana, Sturny, MikaÃ«l, Ebadi, Babak, Ruoccolo, Rafael T., Santos, Robson A.S., Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos

Journal:

The Journal of Sexual Medicine

Year:

2020

File:

PDF, 1.45 MB

2020

37

Pathophysiological role of the renin-angiotensin system on erectile dysfunction

Fraga-Silva, Rodrigo A., Montecucco, Fabrizio, Mach, François, Santos, Robson A. S., Stergiopulos, Nikos

Journal:

European Journal of Clinical Investigation

Year:

2013

Language:

english

File:

PDF, 129 KB

english, 2013

38

The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

Shenoy, Vinayak, Ferreira, Anderson J., Qi, Yanfei, Fraga-Silva, Rodrigo A., Díez-Freire, Carlos, Dooies, Autumn, Jun, Joo Yun, Sriramula, Srinivas, Mariappan, Nithya, Pourang, Dorna, Venugopal, Chang

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

39

An optimized and validated 384-well plate assay to test platelet function in a high-throughput screening format

Martins Lima, Augusto, Bragina, Maiia E., Burri, Olivier, Bortoli Chapalay, Julien, Costa-Fraga, Fabiana P., Chambon, Marc, Fraga-Silva, Rodrigo A., Stergiopulos, Nikolaos

Journal:

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

40

Role of the renin-angiotensin system on abdominal aortic aneurysms

Malekzadeh, Sonaz, Fraga-Silva, Rodrigo A., Trachet, Bram, Montecucco, Fabrizio, Mach, François, Stergiopulos, Nikolaos

Journal:

European Journal of Clinical Investigation

Year:

2013

Language:

english

File:

PDF, 112 KB

english, 2013

41

Ascending Aortic Aneurysm in Angiotensin II–Infused Mice

Trachet, Bram, Piersigilli, Alessandra, Fraga-Silva, Rodrigo A., Aslanidou, Lydia, Sordet-Dessimoz, Jessica, Astolfo, Alberto, Stampanoni, Marco F.M., Segers, Patrick, Stergiopulos, Nikolaos

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2016

Language:

english

File:

PDF, 2.97 MB

english, 2016

42

Diminazene enhances stability of atherosclerotic plaques in ApoE-deficient mice

Fraga-Silva, Rodrigo A., Montecucco, Fabrizio, Costa-Fraga, Fabiana P., Nencioni, Alessio, Caffa, Irene, Bragina, Maiia E., Mach, François, Raizada, Mohan K., Santos, Robson A.S., da Silva, Rafaela F.

Journal:

Vascular Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.60 MB

english, 2015

43

AVE 0991, a non-peptide Mas-receptor agonist, facilitates penile erection

da Costa Gonçalves, Andrey C., Fraga-Silva, Rodrigo A., Leite, Romulo, Santos, Robson A. S.

Journal:

Experimental Physiology

Year:

2013

Language:

english

File:

PDF, 183 KB

english, 2013

44

Nicotinamide phosphoribosyltransferase inhibition reduces intraplaque CXCL1 production and associated neutrophil infiltration in atherosclerotic mice

Nencioni, Alessio, da Silva, Rafaela, Fraga-Silva, Rodrigo, Steffens, Sabine, Fabre, Mathias, Bauer, Inga, Caffa, Irene, Magnone, Mirko, Sociali, Giovanna, Quercioli, Alessandra, Pelli, Graziano, Leng

Journal:

Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 11.60 MB

english, 2014

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